1. Enzymatic Synthesis of Deoxyribonueleic Acid I.
Preparation of Substrates and Partial Purification
of Enzymes from E. coli.
Lehman, I.R., Bessman, M.J., Simms, E.S., and Kornberg A. (1958) J. Biol. Chem.,
233, 163.

2. Chemical Composition of Enzymatically Synthesized DNA.
Lehman, I.R., Zimmerman, S.B., Adler, J. Bessman, M.J. Simms,
E.S. and Kornberg, A. (1958) Proc. Natl. Acad. Sci. USA 44, 1191.

3. Purification and Properties of a Phosphodiesterase.
Lehman, I.R. The Deoxyribonucleases of Ecoli (1960). 235, 1479

4. Linkage of Polynucleotides through Phosphodiester
Bonds by an Enzyme from E. coli.
Olivera, B.M. and Lehman, I.R. (1967). Proc. Natl. Acad. Sci. USA, 57, 1426.

5. DNA Ligase. Isolation and Physical Characterization of the Homogeneous Enzymes from E. coli.
Modrich, P. and Lehman, I.R. (1973). J. Biol. Chem., 248, 7502.

6. Initiation of General Recombination Catalyzed by the
Rec A Protein of E. coli.
McEntee, K. Weinstock, G.M. and Lehman, I.R. (1979). Proc. Natl. Acad.
Sci. USA 76, 2615.

7. Direction and Polarity in Rec A Promoted Branch Migration.
Cox, M.M. and Lehman, I.R. (1981). Proc Natl. Acad. Sci. USA 78, 6018

8. A DNA Binding Protein for an Origin of DNA Replication of Herpes Simplex Virus Type I.
Elias, P., O’Donnell, M.E., Mocarski E.S. and Lehman, I.R. (1986). Proc.
Natl. Acad. Sci. USA, 83, 6322.

9. Rolling Circle DNA Replication in vitro by a Complex of Herpes Simplex Type-1-Encoded Enzymes.
Skaliter, R. and Lehman, I.R. (1994). Proc. Natl. Acad. Sci. USA, 91, 10665.

10. Replication Initiator Protein (UL9) of the Herpes Simplex Virus Type I Binds NFB42 and is Degraded via the Ubiquitin-Proteosome Pathway.
Eom, C.Y., and Lehman, I.R. (2003). Proc. Natl. Acad. Sci. USA, 100, 9803.


1. Kornberg, A., Lehman, I. R., Bessman, M. J., and Simms, E. S. Enzymic Synthesis of Deoxyribonucleic Acid. Biochim. et Biophys. Acta 21:197 (1956).

2. Lehman, I. R. and Herriott, R. M. The Protein Coats or "Ghosts" of Coliphage T2. III. Metabolic Studies of E. coli B Infected with T2 Bacteriophage "Ghosts". J. Gen. Physiol. 41:1067 (1958).

3. Lehman, I. R., Bessman, M. J., Simms, E. S., and Kornberg, A. Enzymatic Synthesis of Deoxyribonucleic Acid. I. Preparation of Substrates and Partial Purification of an Enzyme from E. coli. J. Biol. Chem. 233:163 (1958).

4. Bessman, M. J., Lehman, I. R., Simms, E. S., and Kornberg, A. Enzymatic Sythesis of Deoxyribonucleic Acid. II. General Properties of the Reaction. J. Biol. Chem. 233:171 (1958).

5. Bessman, M. J., Lehman, I. R., Adler, J., Zimmerman, S. B., Simms, E. S., and Kornberg, A. Enzymatic Synthesis of Deoxyribonucleic Acid. III. The Incorporation
of Pyrimidine and Purine Analogues into DNA. Proc. Natl. Acad. Sci., Wash. 44:623 (1958).

6. Adler, J., Lehman, I. R., Bessman, M. J., Simms, E. S., and Kornberg, A. Enzymatic Synthesis of Deoxyribonucleic Acid. IV. Linkage of Single Deoxyribonucleotides to
the Deoxyribonucleoside Ends of DNA. Proc. Natl. Acad. Sci. 44:641 (1958).

7. Lehman, I. R., Zimmerman, S. B., Adler, J., Bessman, M. J., Simms, E. S., and Kornberg, A. Enzymatic Synthesis of Deoxyribonucleic Acid. V. Chemical
Composition of Enzymatically Synthesized DNA. Proc. Natl. Acad. Sci., Wash.
44:1191 (1958).

8. Kornberg, S. R., Lehman, I. R., Bessman, M. J., Simms, E. S., and Kornberg, A. Enzymatic Cleavage of Deoxyguanosine Triphosphate to Deoxyguanosine and Tripolyphosphate. J. Biol. Chem. 233:159 (1958).

9. Schachman, H. K., Adler, J., Radding, C. M., Lehman, I. R., and Kornberg, A. Enzymatic Synthesis of Deoxyribonucleic Acid. VII Synthesis of a Polymer of Deoxyadenylate and Deoxythymidylate. J. Biol. Chem. 235:3242 (1960).

10. Lehman, I. R. Enzymatic Synthesis of Deoxyribonucleic Acid. Ann. N. Y. Acad.
Sci. 81:745 (1959).

11. Lehman, I. R. The Deoxyribonucleases of E. coli. I. Purification and Properties
of a Phosphodiesterase. J. Biol. Chem. 235: 1479 (1960).

12. Lehman, I. R. and Pratt, E. A. On the Structure of the Glucosylated Hydro-xymethylcytosine Nucleotides of Coliphages T2, T4 and T6. J. Biol. Chem.
235:3254 (1960).

13. Lehman, I. R., Roussos, G. G., and Pratt, E. A. The Deoxyribonucleases of E.
coli. II. Purification and Properties of an RNA-inhibitable Endonuclease. J. Biol.
Chem. 237:819 (1962).

14. Lehman, I. R., Roussos, G. G., and Pratt, E. A. The Deoxyribonucleases of E. coli.
III. Studies on the Nature of the Inhibition of Endonuclease by RNA. J. Biol. Chem.
237:829 (1962).


15. Kuno, S. and Lehman, I. R. Gentiobiose, A Constituent of DNA from Coliphage
T6. J. Biol. Chem. 237:1266 (1962).


16. Pratt, E. A., Kuno, S., and Lehman, I. R. Glucosylation of the DNA in Hybrids
of Coliphages T2 and T4. Biochim. et Biophys. Acta 68:108 (1963).


17. Lehman, I. R. The Nucleases of E. coli in "Progress in Nucleic Acid Research"
(W. Cohn and J. N. Davidson, eds.) Vol. II. Academic Press, New York, p. 83 (1963).


18. Lehman, I. R. DNA Synthesis (Bacterial) in "Methods in Enzymology" (N. O.
Kaplan and S. P. Colowick, eds.) Vol. VI. Academic Press, New York, p. 34 (1963).

19. Lehman, I. R. Nucleases of E. coli I. A DNA-Specific Phosphodiesterase in
"Methods in Enzymology" (N. O. Kaplan and S. P. Colowick, eds.) Vol. VI.
Academic Press, New York, p. 40 (1963).


20. Lehman, I. R. Nucleases of E. coli II. An RNA-Inhibitable Endonuclease in
"Methods in Enzymology" (N. O. Kaplan and S. P. Colowick, eds.) Vol. V.
Academic Press, New York, p. 44 (1963).


21. Lehman, I. R., and Nussbaum, A. L. The Deoxyribonucleases of E. coli. IV. An Exonuclease Activity Present in Purified Preparations of DNA Polymerase. J. Biol. Chem. 239:233 (1964).

22. Lehman, I. R., and Nussbaum, A. L. The Deoxyribonucleases of E. coli. V. On
the Specificity of Exonuclease-I (Phosphodiesterase). J. Biol. Chem. 239:2628 (1964).


23. Richardson, C. C., Lehman, I. R., and Kornberg, A. Deoxyribonucleic Acid Phosphatase - Exonuclease from E. coli. II Characterization of the Exonuclease
Activity. J. Biol. Chem. 239:251 (1964).


24. Shortman, K. D., and Lehman, I. R. The Deoxyribonucleases of E. coli. VI.
Changes in Enzyme Activities in Response to Alterations in Physiological State of
the Cells. J. Biol. Chem. 239:2964 (1964).


25. Linn, S., and Lehman, I. R. An Endonuclease from N. Crassa Specific for Polynucleotides Lacking an Ordered Structure. I. Purification and Properties of
the Enzyme. J. Biol. Chem. 240:1287 (1965).


26. Linn, S., and Lehman, I. R. An Endonuclease from N. Crassa Specific for Polynucleotides Lacking an Ordered Structure. II. Studies of Enzyme Specificity.
J. Biol. Chem. 240:1294 (1965).


27. Kerr, I. M., Pratt, E. A., and Lehman, I. R. Exonucleolytic Degradation of High Molecular Weight DNA and RNA to Nucleoside 3'-Phosphates by a Nuclease from B. subtilis. Biochem. Biophys. Res. Comm. 20:154 (1965).

28. deWaard, A., Paul, A. V., and Lehman, I. R. The Structural Gene for Deoxyribonucleic Acid Polymerase in Bacteriophages T4 and T5. Proc. Natl. Acad.
Sci. USA 54:1241 (1965).


29. Lehman, I. R., Linn, S., and Richardson, C. C. Nucleases as Reagents in the
Study of Nucleic Acid Structure. Federation Proc. (Symposia) 24: 1466 (1965).

30. Linn, S., and Lehman, I. R. An Endonuclease from Mitochondria of Neurospora crassa. J. Biol. Chem. 241:2694 (1966).

31. Paul, A. V., and Lehman, I. R. The Deoxyribonucleases of E. coli. VII. A Deoxyribonuclease Induced by Infection with Phage T5. J. Biol. Chem. 241:3441
91966).


32. Lehman, I. R. Exonuclease I (phosphodiesterase) from Escherichia coli in "Procedures in Nucleic Acid Research" (G. L. Cantoni and D. R. Davies, eds.)
Harper and Row, New York, Vol. I, p. 203 (1966).

33. deWaard, A., and Lehman, I. R. Endonuclease I from Escherichia coli in "Procedures in Nucleic Acid Research" (G. L. Cantoni and D. R. Davies, eds.)
Harper and Row, New York, Vol. I, p. 122 (1966).

34. Lehman, I. R. Deoxyribonucleases: Their Relationship to Deoxyribonucleic
Acid Synthesis. Ann. Reviews of Biochem. 36:645 (1967).


35. Kerr, I. M., Chien, J. R., and Lehman, I. R. Exonucleolytic Degradation of High Molecular-Weight Deoxyribonucleic Acid and Ribonucleic Acid by an Enzyme from Bacillus subtilis. J. Biol. Chem. 242:2700 (1967).

36. Olivera, B. M., and Lehman, I. R. Linkage of Polynucleotides through Phosphodiester Bonds by an Enzyme from Echerichia coli. Proc. Natl. Acad. Sci.,
Wash. 57:1426 (1967).

37. Olivera, B. M., and Lehman, I. R. Diphosphopyridine Nucleotide: A Cofactor
for the Polynucleotide-Joining Enzyme from Escherichia coli. Proc. Natl. Acad. Sci.,
Wash. 57:1700 (1967).


38. Little, J. W., Lehman, I. R., and Kaiser, A. D. An Exonuclease Induced by Bacteriophage λ. I. Preparation of the Crystalline Enzyme. J. Biol. Chem. 242:672 (1967).

39. Little, J. W. An Exonuclease Induced by Bacteriophage λ. II. Nature of the Enzymatic Reaction. J. Biol. Chem. 242:679 (1967).

40. Hall, Z. W., and Lehman, I. R. An In vitro Transversion by a Mutationally
Altered T4-induced DNA Polymerase. J. Mol. Biol. 36:321 (1968).


41. Olivera, B. M., and Lehman, I. R. Enzymatic Joining of Polynucleotide. III. The Polydeoxyadenylate. Polydeoxythymidylate Homopolymer Pair. J. Mol. Biol. 36:261 (1968).

42. Olivera, B. M., Scheffler, I. E., and Lehman, I. R. Enzymatic Joining of Polynucleotides. IV. Formation of a Circular Deoxyadenylate - Deoxythymidylate Copolymer. J. Mol. Biol. 36:275 (1968).

43. Olivera, B. M., Hall, Z. W., and Lehman, I. R. Enzymatic Joining of
Polynucleotides. V. A DNA-Adenylate Intermediate in the Polynucleotide Joining
Reaction. Proc. Natl. Acad. Sci. USA 61:237 (1968).


44. Olivera, B. M., Hall, Z. W., Anraku, Y., Chien, J., and Lehman, I. R. On the Mechanism of the Polynucleotide Joining Reaction. Cold Spring Harb. Symp. Quant. Biol. 33:27 (1968).

45. Hall, Z. W., and Lehman, I. R. Enzymatic Joining of Polynucleotides. VI. Activity
of a Synthetic Adenylylated Polydeoxynucleotide in the Reaction. J. Biol. Chem.
244:43 (1969).


46. Anraku, N., and Lehman, I. R. Enzymatic Joining of Polynucleotides. VII. Role
of the T4-induced Ligase in the Formation of Recombinant Molecules. J. Mol. Biol.
46:467 (1969).


47. Anraku, N., Anraku, Y., and Lehman, I. R. Enzymatic Joining of Polynucleotides. VIII The Structure of Hybrids of Parental T4 DNA Molecules, J. Mol. Biol. 46:481 (1969).

48. Kelly, R. B., Cozzarelli, N. R., Deutscher, M. P. Lehman, I. R., and Kornberg,
A. Enzymatic Synthesis of Deoxyribonucleic Acid. XXXII. Replication of Duplex Deoxyribonucleic Acid by Polymerase at a Single Strand Break. J. Biol. Chem.
245:39 (1970).


49. Modrich, P., and Lehman, I. R. Enzymatic Joining of Polynucleotides. IX. A Simple and Rapid Assay of Polynucleotide Joining (Ligase) Activity by Measurement of Circle Formation from Linear Deoxyadenylate-Deoxythymidylate Copolymer. J. Biol. Chem. 245:3526 (1970).

50. Modrich, P., and Lehman, I. R. Enzymatic Characterization of a Mutant of Escherichia coli with an Altered DNA Ligase. Proc. Natl. Acad. Sci. USA 68:1002 (1971).

51. Lehman, I. R. Bacterial Deoxyribonucleases in "The Enzymes" (Paul D. Boyer,
ed.) Academic Press, Inc., New York, Vol. IV, p. 251 (1971).


52. Paoletti, C., LePecq, J. B., and Lehman, I. R. The Use of Ethidium Bromide - Circular DNA Complexes for the Fluorometric Analysis of Breakage and Joining of DNA. J. Mol. Biol. 55:75 (1971).

53. Gumport, R. I., and Lehman, I. R. Structure of the DNA Ligase-Adenylate Intermediate: Lysine (-amino)-Linked Adenosine Monophosphoramidate. Proc.
Natl. Acad. Sci. USA 68:2559 (1971).


54. Broker, T. R., and Lehman, I. R. Branched DNA Molecules: Intermediates in
T4 Recombination. J. Mol. Biol. 60:131 (1971).

55. Swartz, M. N., Nakamura, H., and Lehman, I. R. Activation of a Defective
DNA Polymerase in a Temperature-Sensitive Mutant of Bacteriophage T4.
Virology 47:338 (1972).


56. Huang, W. M., and Lehman, I. R. On the Exonuclease Activity of Phage T4
DNA Polymerase. J. Biol. Chem. 247:3139 (1972).


57. Modrich, P., Wang, J. C., and Lehman, I. R. Enzymatic Joining of
Polynucleotides. XI. Reversal of Escherichia coli Deoxyribonucleic Acid Ligase
Reaction. J. Biol. Chem. 247:6370 (1972).

58. Lehman, I. R., and Chien, J. R. DNA Polymerase I Activity in Polymerase I
Mutants of Escherichia coli in "DNA Synthesis In Vitro.". (R. D. Wells and R. B.
Inman, eds.) University Park Press, Baltimore, MD, p. 3 (1973).

59. Huang, W. M., and Lehman, I. R. On the Direction of Translation of the T4
DNA Polymerase Gene In vivo. J. Biol. Chem. 247: 7663 (1972).


60. Konrad, B., Modrich, P., and Lehman, I. R. Genetic and Enzymatic
Characterization of a Conditional Lethal Mutant of E. coli K12 with a Temperature-
Sensitive DNA Ligase. J. Mol. Biol. 77: 519 (1973).


61. Broker, T. R. An Electron Microscopie Analysis of Pathways for T4 DNA Recombination. J. Mol. Biol. 81:1 (1973).

62. Modrich, P., Anraku, Y., and Lehman, I. R. Deoxyribonucleic Acid Ligase.
Isolation and Physical Characterization of the Homogeneous Enzyme from
Escherichia coli. J. Biol. Chem. 248:7495 (1973).


63. Modrich, P., and Lehman, I. R. Deoxyribonucleic Acid Ligase. A Steady State
Kenetic Analysis of the Reaction Catalyzed by the Enzyme from Escherichia coli.
J. Biol. Chem. 248:7502 (1973).


64. Lehman, I. R., and Chien, J. R. Persistence of DNA Polymerase I and its 5' → 3'
Exonuclease Activity in PolA Mutants of Escherichia coli K12. J. Biol. Chem.
248:7717 (1973).


65. Friedberg, E. C., and Lehman, I. R. Excision of Thymine Dimers by Proteolytic
and Amber Fragments of E. coli DNA Polymerase I. Biochem. and Biophys. Res.
Comm. 58:132 (1974).


66. Konrad, E. B., and Lehman, I. R. A conditional Lethal Mutant of Escherichia coli. K12 Defective in the 5' → 3' Exonuclease Associated with DNA Polymerase I. Proc. Natl. Acad. Sci. U.S.A. 71:2048 (1974).

67. Konrad, E. B., Modrich, P., and Lehman, I. R. DNA Synthesis in Strains of E.
coli K12 with Temperature Sensitive DNA Ligase and DNA Polymerase I. J. Mol.
Biol. 90:115-126 (1974).


68. Lehman, I. R. DNA Ligase: Structure, Mechanism, and Function. Science
186:790-797 (1974).

69. Lehman, I. R. T4 DNA Polymerase in Methods in Enzymology (L. Grossman
and K. Moldave, eds.) Academic Press, New York, Vol. 29, Part E, p. 46 (1974).


70. Lehman, I. R. "DNA Joining Enzymes (Ligases)" in The Enzymes, Vol. X., 3rd Edition, Acadmic Press, New York, p. 237-259 (1974).

71. Kushner, S. R. In Vivo Studies of Temperature-Sensitive recB and recC Mutants.
J. Bact. 120:1213 (1974).


72. Kushner, S. R. Differential Thermolability of Exonuclease and Endonuclease Activities of the recBC Nuclease Isolated from Thermosensitive recB and recC
Mutants. J. Bact. 120:1219 (1974).


73. Konrad, E. B., and Lehman, I. R. Novel Mutants of E. coli that Accumulate Very Small DNA Replicative Intermediates. Proc. Natl. Acad. Sci. 72:2150 (1975).

74. Thorner, J., Huang, W., and Lehman, I. R. Energy-Dependent Activation of the Temperature-Sensitive DNA Polymerases Induced by Bacteriophage T4 Gene 43 Mutants. Virology 68:338-348 (1975).

75. Uyemura, D., Bambara, R., and Lehman, I. R. On the Processive Mechanism of Escherichia coli DNA Polymerase I. J. Biol. Chem. 250:8577 (1975).

76. Cameron, J. R., Panasenko, S. M., Lehman, I. R., and Davis, R. W. In Vitro Construction of Bacteriophage λ Carrying Segments of the Escherichia coli Chromosome: Selection of Hybrids Containing the Gene for DNA Ligase. Proc.
Natl. Acad. Sci. 72:3416-3420 (1975).


77. Uyemura, D. G., Konrad, E. B., and Lehman, I. R. Two Temperature-Sensitive
PolA Mutants: An Approach to the Role In Vivo of DNA Polymerase I in Molecular Mechanisms for Repair of DNA, Part A (Hanawalt, P.C., and Setlow, R. B., eds.)
Plenum Publishing Co., New York, p. 209-211 (1975).


78. Konrad, E. B., and Lehman, I. R. Mutants of Escherichia coli Defective in the Joining of Nascent DNA Fragments in DNA Synthesis and Its Regulation (M.
Goulian and P. Hanawalt, eds.) W. A. Benjamin, p. 304 (1975).

79. Panasenko, S. M., Modrich, P., and Lehman, I. R. Modification of Escherichia
coli DNA Ligase by Cleavage with Trypsin. J. Biol. Chem. 251:3432 (1976).


80. Uyemura, D., and Lehman, I. R. Biochemical Characterization of Mutant Forms
of DNA Polymerase I from Escherichia coli: I. The PolA12 Mutation. J. Biol. Chem.
251:4078-4084 (1976).


81. Uyemura, D., Eichler, D. C., and Lehman, I. R. Biochemical Characterization of Mutant Forms of DNA Polymerase I from Escherichia coli: II. The PolAex 1
Mutation. J. Biol. Chem. 251:4085-4089 (1976).


82. Bambara, R. A., Uyemura, C., and Lehman, I. R. On the Processive Mechanism
of Escherichia coli DNA Polymerase I: Delayed Initiation of Polymerization. J. Biol.
Chem. 251:4090 (1976).


83. Lehman, I. R., and Uyemura, D. G. DNA Polymerase I: Essential Replication Enzyme. Science 193:963-968 (1976).

84. Eichler, D. C., and Lehman, I. R. On the Role of ATP in Phosphodiester Bond Hydrolysis Catalyzed by the RecBC Deoxyribonuclease of Escherichia coli. J. Biol. Chem. 252:499-503 (1977).

85. Tye, B. K., Nyman, P. O., Lehman, I. R., Hochhauser, S., and Weiss, B. Transient Accumulation of Okazaki Fragments as a Result of Uracil Incorporation into Nascent DNA. Proc. Natl. Acad. Sci. 74:154-157 (1977).

86. Panasenko, S. M., Cameron, J. R., Davis, R. W., and Lehman, I. R. Five Hundred-Fold Overproduction of E. coli DNA Ligase After Induction of a Lysogen Containing Hybrid Lambda DNA Constructed in vitro. Science 196:188-189 (1977).

87. Bambara, R. A., Uyemura, D., and Choi, T. On the Processive Mechanism of Escherichia coli DNA Polymerase I: Quantitative Assessment of Processivity. J. Biol. Chem. 253:413-423 (1978).

88. Tye, B. K., and Lehman, I. R. Excision Repair of Uracil Incorporated in DNA as
a Result of a Defect in dUTPase. J. Mol. Biol. 117:293-306 (1977).


89. Konrad, E. B. Method for Isolation of E. coli Mutants with Enhanced
Recombination between Chromosomal Duplications. J. Bact. 130:167-172 (1977).

90. Lehman, I. R., and Tye, B. K. Excision Repair of Uracil in DNA and Its
Contribution to the Pool of Okazaki Fragments in DNA Synthesis, Present and
Future (I. Molineux and M. Kohiyama, eds.) Plenum Press, New York, p. 281-298 (1978).

91. Tye, B. K., Chien, J., Lehman, I. R., Duncan, B. K., and Warner, H. R. Uracil Incorporation: A Source of Pulse-Labeled DNA Fragments in the Replication of the E. coli Chromosome. Proc. Natl. Acad. Sci. 75:233-237 (1978).

92. Panasenko, S. M., Alazard, R. J., and Lehman, I. R. A Simple, Three-Step
Procedure for the Large-Scale Purification of DNA Ligase from a Hybrid Lambda Lysogen Constructed In vitro. J. Biol. Chem. 253:4590-4592 (1978).

93. Tye, B. K., Nyman, P. O., and Lehman, I. R. Excision Repair of Uracil During Replication of φX174 DNA In vitro. Biochem. Biophys. Res. Comm. 82:434-441
(1978).

94. Lehman, I. R., Tye, B. K., and Nyman, P. O. Excision-Repair of Uracil in DNA.
Its Implications for the Discontinuous Replication of DNA In vivo and In vitro. Cold
Spring Harbor Symposia on Quant. Biol. 43:221-230 (1979).

95. Weinstock, G. M., McEntee, K., and Lehman, I. R. ATP-Dependent Renaturation
of DNA Catalyzed by the RecA Protein of E. coli. Proc. Natl. Acad. Sci. USA
76:126-130 (1979).

96. McEntee, K., Weinstock, G. M., and Lehman, I. R. Initiation of General Recombination Catalyzed by the RecA Protein of E. coli. Proc. Natl. Acad. Sci.
U.S.A. 76:2615-2619 (1979).

97. Banks, G. R., Boezi, J. A. and Lehman, I. R. A High Molecular Weight DNA Polymerase from Drosophila melanogaster Embryos. J. Biol. Chem. 254:9886-9892.

98. McEntee, K., Weinstock, G. M., and Lehman, I. R. RecA Protein-catalyzed
Strand Assimilation: Stimulation by E. coli Single-stranded DNA-binding Protein.
Proc. Natl. Acad. Sci. U.S.A. 77:857-861 (1980).

99. Villani, G., Sauer, B. and Lehman, I. R. DNA Polymerase α from Drosophila melanogaster Embryos. Subunit Structure. J. Biol. Chem. 255:9479-9483 (1980).

100. Lehman, I. R. On the Role of the recA Protein in General Recombination in
The Evolution of Protein Structure and Function, Symposium honoring Emil Smith,
Academic Press, New York (1980).

101. Cox, M. M. and Lehman, I.R. Renaturation of DNA: A Novel Reaction of
Histones. Nucl. Acids Res. 9:389-400 (1981).

102. Cox, M. M., McEntee, K. and Lehman, I. R. A Simple and Rapid Procedure for
the Large Scale Purification of the RecA Protein of E. coli. J. Biol. Chem. 256:4676-
4678 (1981).

103. McEntee, K., Weinstock, G. M. and Lehman, I. R. DNA and Nucleoside Triphosphate Binding Properties of RecA Protein from E. coli in Progress in Nucleic Acid Research and Molecular Biology, Vol. 26:265-279 (Waldo E. Cohn, ed.),
Academic Press, N.Y. (1981).

104. Cox, M.M. and Lehman, I.R. RecA Protein of Escherichia coli Promotes
Branch Migration, a Kinetically Distinct Phase of DNA Strand Exchange. Proc.
Natl. Acad. Sci. USA 78:3433-3437 (1981).

105. Villani, G., Fay, P.J., Bambara, R.A. and Lehman, I.R. Elongation of RNA-
primed DNA Templates by DNA Polymerase α from Drosophila melanogaster
Embryos. J. Biol. Chem. 256:8202-8207 (1981).

106. Weinstock, G.M. and McEntee, K. RecA Protein-dependent Proteolysis of Bacteriophage λ Repressor. J. Biol. Chem. 256:10883-10888 (1981).

107. Cox, M.M. and Lehman, I.R. Directionality and Polarity in RecA Protein-
promoted Branch Migration. Proc. Natl. Acad. Sci. USA 78:6018-6022 (1981).

108. Weinstock, G. M., McEntee, K. and Lehman, I. R. Hydrolysis of Nucleoside Triphosphates Catalyzed by the RecA Protein of E. coli. Characterization of ATP Hydrolysis. J. Biol. Chem. 256:8829-8834 (1981).

109. McEntee, K., Weinstock, G. M. and Lehman, I. R. Binding of the RecA Protein
of E. coli to Single- and Double-stranded DNA. J. Biol. Chem. 256:8835-8844 (1981).

110. Weinstock, G. M., McEntee, K. and Lehman, I. R. Hydrolysis of Nucleoside Triphosphates Catalyzed by the RecA Protein of E. coli. Steady State Kinetic
Analysis of ATP Hydrolysis. J. Biol. Chem. 256:8845-8849 (1981).

111. Weinstock, G. M., McEntee, K. and Lehman, I. R. Interaction of the RecA
Protein of E. coli with Adenosine 5'-0-(3-thiotriphosphate). J. Biol. Chem.
256:8850-8855 (1981).


112. Weinstock, G. M., McEntee, K. and Lehman, I. R. Hydrolysis of Nucleoside Triphosphates Catalyzed by the RecA Protein of E. coli. Hydrolysis of UTP. J. Biol.
Chem. 256:8856-8858 (1981).


113. McEntee, K. and Weinstock, G. M. tif Mutation Alters Polynucleotide
Recognition by the RecA Protein of E. coli. Proc. Natl. Acad. Sci. U.S.A. 78:6061-
6065 (1981).


114. Weinstock, G. M. and McEntee, K. RecA Protein-dependent Proteolysis of Bacteriophage λ Repressor. Characterization of the Reaction and Stimulation by
DNA-binding Proteins. J. Biol. Chem. 256:10883-10888 (1981).


115. Lehman, I. R. DNA Polymerase I of Escherichia coli. In The Enzymes, Vol.
XIV (P. Boyer, ed.), p. l5-37, Academic Press, N. Y. (1981).

116. Lehman, I. R. T-Phage DNA Polymerases. In The Enzymes, Vol. XIV
(P. Boyer, ed.), p. 51-65, Academic Press, N. Y. (1981).

117. Lehman, I. R. Endonucleases Specific for Single-Stranded Polynucleotides. In
The Enzymes, Vol. XIV (P. Boyer, ed.), p. 193-201, Academic Press, N. Y. (1981).


118. Conaway, R. C. and Lehman, I. R. A DNA Primase Activity Associated with
DNA Polymerase α from Drosophila melanogaster. Proc. Natl. Acad. Sci. USA
79:2523-2527 (1982).


119. Livneh, Z. and Lehman, I. R. Recombinational Bypass of Pyrimidine Dimers Promoted by the RecA Protein of Escherichia coli. Proc. Natl. Acad. Sci. USA
79:3171-3175 (1982).


120. Cox, M. M. and Lehman, I. R. RecA Protein-promoted DNA Strand Exchange. Stable Complexes of RecA Protein and Single-stranded DNA Formed in the Presence
of ATP and Single-stranded DNA Binding Protein. J. Biol. Chem. 257:8523-8532
(1982).


121. Sauer, B. L. and Lehman, I. R. Immunological Comparison of Purified DNA Polymerase α from Embryos of Drosophila melanogaster with Forms of the
Enzyme Present in vivo. J. Biol. Chem. 257:12394-12398 (1982).


122. Cox, M. M., Soltis, D. A., Lehman, I. R., DeBrosse, C. and Benkovic, S. J. ADP-mediated Dissociation of Stable Complexes of RecA Protein and Single-stranded
DNA. J. Biol. Chem. 258:2586-2592 (1983).


123. Cox, M. M., Soltis, D. A., Livneh, Z. and Lehman, I. R. On the Role of Single-stranded DNA Binding Protein in RecA protein-promoted DNA Strand Exchange. J. Biol. Chem. 258:2577-2585 (1983).

124. Cox, M. M., Soltis, D. A., Livneh, Z. and Lehman, I. R. DNA Strand Exchange Promoted by RecA Protein and Single-stranded DNA-binding Protein of Escherichia
coli. Cold Spring Harbor Symp. on Quant. Biol. XLVII, 803-810 (1983).


125. Kaguni, L. S., Rossignol, J.-M., Conaway, R. C. and Lehman, I. R. Isolation of
an Intact DNA Polymerase-primase from Embryos of Drosophila melanogaster.
Proc. Natl. Acad. Sci. USA 80:2221-2225 (1983).


126. Soltis, D. A., Cox, M. M., Livneh, Z. and Lehman, I. R. A Stable RecA Protein-Single-stranded DNA Complex: An Intermediate in DNA Strand Exchange in Mechanisms of DNA Replication and Recombination (Cozzarelli, N. R., ed.), Alan
R. Liss, Inc., New York, p. 709-721 (1983).


127. Kaguni, L. S., Rossignol, J.-M., Conaway, R. C. and Lehman, I. R. The DNA Polymerase-Primase Complex of Drosophila Melanogaster Embryos in Mechanisms
of DNA Replication and Recombination (Cozzarelli, N. R., ed.), Alan R. Liss, Inc.,
New York, p. 495-510 (1983).

128. Kaguni, L. S., Rossignol, J.-M., Conaway, R. C., Banks, G. R. and Lehman,
I. R. Association of DNA Primase with the β−α Subunits of DNA Polymerase α from
Drosophila melanogaster Embryos. J. Biol. Chem. 258:9037-9039 (1983).

129. Soltis, D.A. and Lehman, I.R. An Unpaired 3’ Terminus Stimulates RecA
Protein-promoted DNA Strand Exchange. J. Biol. Chem. 258:14073-14075 (1983).


130. Kaguni, L. S., DiFrancesco, R. A. and Lehman, I. R. The DNA Polymerase-
Primase from Drosophila melanogaster Embryos. Rate and Fidelity of
Polymerization on Single-stranded DNA Templates. J. Biol. Chem. 259:9314-9319 (1984).


131. Soltis, D. A. and Lehman, I. R. RecA Protein-promoted DNA Strand Exchange. Effect of Ionic Strength. J. Biol. Chem. 259:12020-12024 (1984).

132. Bryant, F. R., Riddles, P. W. and Lehman, I. R. Studies of the Mechanism of
DNA Pairing by the RecA Protein of Escherichia coli. Cold Spring Harbor Symp.
Quant. Biol. XLIX, 535-539 (1984).


133. Bryant, F. R., Taylor, A. R. and Lehman, I. R. Interaction of the RecA Protein
of Escherichia coli with Single-stranded DNA. J. Biol. Chem. 260:1196-1201 (1985).


134. Bryant, F. A. and Lehman, I. R. On the Mechanism of Renaturation of Complementary DNA Strands by the RecA Protein of Escherichia coli. Proc. Natl.
Acad. Sci. USA 82:297-301 (1985).


135. Riddles, P. W. and Lehman, I. R. The Formation of Paranemic and Plectonemic Joints between DNA Molecules by the RecA and Single-stranded DNA-binding
Proteins of Escherichia coli. J. Biol. Chem. 260:165-169 (1985).


136. Riddles, P. W. and Lehman, I. R. The Formation of Plectonemic Joints by the
RecA Protein of Escherichia coli. Requirement for ATP Hydrolysis. J. Biol. Chem.
260:170-173 (1985).


137. DiFrancesco, R. A. and Lehman, I. R. Interaction of Ribonuclease H from Drosophila melanogaster Embryos with DNA Polymerase-Primase. J. Biol. Chem.
260:14764-14770 (1985).


138. Julin, D. A., Riddles, P. W. and Lehman, I. R. On the Mechanism of Pairing of Single- and Double-stranded DNA Molecules by the RecA and Single-stranded DNA-
binding Proteins of Escherichia coli. J. Biol. Chem. 261:1025-1030 (1986).


139. Greenleaf, A.L., Kelly J.L. and Lehman, I.R. Yeast RPO41 Gene Product is Required for Transcription and Maintenance of the Mitochondrial Genome. Proc.
Natl. Acad. Sci. USA 83: 3391-3394 (1986).


140. Kelly, J. L. and Lehman, I. R. Yeast Mitochondrial RNA Polymerase.
Purification and Properties of the Catalytic Subunit. J. Biol. Chem. 261:10340-
10347 (1986).


141. Kelly, J. L., Greenleaf, A. L. and Lehman, I. R. Isolation of the Nuclear Gene
Encoding a Subunit of the Yeast Mitochondrial RNA Polymerase. J. Biol. Chem.
261:10348-10351 (1986).


142. Elias, P., O'Donnell, M. E., Mocarski, E. S. and Lehman, I. R. A DNA Binding Protein Specific for an Origin of Replication of Herpes Simplex Virus Type 1. Proc.
Natl. Acad. Sci. USA 83:6322-6326 (1986).


143. Bryant, F. R. and Lehman, I. R. ATP-independent Renaturation of
Complementary DNA Strands by the Mutant RecA1 Protein from Escherichia coli.
J. Biol. Chem. 261:12988-12993 (1986).


144. Lehman, I. R., DiFrancesco, R. A., Kaguni, L. S. and Cotterill, S. Assembly of
a DNA Replication Complex from Drosophila melanogaster Embryos in Mechanisms
of DNA Replication and Recombination, Vol 47 (T. Kelly and R. McMacken, eds.),
Alan R. Liss, Inc., New York (1986), pp. 89-100.

145. O'Donnell, M. E., Elias, P. and Lehman, I. R. Processive Replication of Single-stranded DNA Templates by the Herpes Simplex Virus-induced DNA Polymerase. J.
Biol. Chem. 262: 4252-4259 (1987).

146. O'Donnell, M. E., Elias, P., Funnell, B. E. and Lehman, I. R. Interaction between
the DNA Polymerase and Single-stranded DNA Binding Protein (ICP8) of Herpes
Simplex Virus-1. J. Biol. Chem. 262:4260-4266 (1987).


147. Cox, M. M. and Lehman, I. R. Enzymes of General Recombination. Ann. Rev.
Biochem. 56:229-262 (l987).


148. Julin, D. A. and Lehman, I. R. Photoaffinity labeling of the RecBCD enzyme of Escherichia coli with 8-azidoadenosine 5'-triphosphate. J. Biol. Chem. 262:9044-9051
(1987).


149. Cotterill, S. M., Reyland, M. E., Loeb, L. A. and Lehman, I. R. A cryptic proofreading 3'→5' exonuclease associated with the polymerase subunit of the
DNA polymerase-primase from Drosophila melanogaster. Proc. Natl. Acad. Sci.
USA 84:5635-5639 (1987).


150. Cotterill, S. M., Chui, G. and Lehman, I. R. DNA Polymerase-Primase from Embryos of Drosophila melanogaster. The DNA Polymerase Subunit. J. Biol.
Chem. 262:16100-16104 (1987).


151. Cotterill, S. M., Chui, G. and Lehman, I. R. DNA Polymerase-Primase from Embryos of Drosophila melanogaster. DNA Primase Subunits. J. Biol. Chem.
262:16105-16108 (1987).


152. Elias, P. and Lehman, I. R. Interaction of origin binding protein with an origin
of replication of herpes simplex virus 1. Proc. Natl. Acad. Sci. USA 85:2959-2963
(1988).


153. Reyland, M. E., Lehman, I. R. and Loeb, L. A. Specificity of Proofreading by
the 3'→5' Exonuclease of the DNA Polymerase-Primase of Drosophila melanogaster.
J. Biol. Chem. 263:6518-6524 (1988).


154. Cotterill, S. M., Reyland, M. E., Loeb, L. A. and Lehman, I. R. Enzymatic
Activities Associated with the Polymerase Subunit of the DNA Polymerase-Primase
of Drosophila melanogaster. Cancer Cells 6/ Eukaryotic DNA Replication , Cold
Spring Harbor Laboratory, pp. 367-371 (1988).

155. Kaguni, L. S. and Lehman, I. R. Eukaryotic DNA polymerase-primase:
structure, mechanism and function." (Review) Biochim. Biophys. Acta. 950:87-101 (1988).


156. Crute, J. J., Mocarski, E. S. and Lehman, I. R. A DNA helicase induced by
herpes simplex virus type 1. Nucleic Acids Res. 16:6585-6596 (1988).


157. Reyland, M. E., Cotterill, S. M., Lehman, I. R. and Loeb, L. A. Fidelity of
DNA Polymerase α in Mechanisms and Consequences of DNA Damage Processing,
Alan R. Liss, Inc., p. 529-537 (1988).

158. Lehman, I. R. and Kaguni, L. S. DNA Polymerase α (minireview). J. Biol.
Chem. 264:4265-4268 (1989).


159. Crute, J. J., Tsurumi, T., Zhu, L., Weller, S. K., Olivo, P. D., Challberg, M. D., Mocarski, E. S. and Lehman, I. R. Herpes simplex virus 1 helicase-primase: A
complex of three herpes-encoded gene products. Proc. Natl. Acad. Sci. USA
86:2186-2189 (1989).


160. Crute, J. J. and Lehman, I. R. Herpes simplex-1 DNA polymerase: Identification
of an Intrinsic 5' → 3' Exonuclease with Ribonuclease H Activity. J. Biol. Chem. 264:19266-19270 (1989).


161. Dodson, M. S., Crute, J. J., Bruckner, R. C. and Lehman, I. R. Overexpression
and Assembly of the Herpes Simplex Virus Type 1 Helicase-Primase In insect Cells. J.
Biol. Chem. 264:20835-20838 (1989).


162. Tsurumi, T. and Lehman, I. R. Release of RNA polymerase from Vero cell mitochondria following herpes simplex virus-1 infection. J. Virol. 64:450-452
(1990).


163. Hernandez, T. R. and Lehman, I. R. Functional Interaction between the
Herpes Simplex-1 DNA Polymerase and UL42 Protein. J. Biol. Chem.
265:11227-11232 (1990)
.

164. Bruckner, R. C., Crute, J. J., Dodson, M. S. and Lehman, I. R. The Herpes
Simplex Virus 1 Origin Binding Protein: A DNA Helicase. J. Biol. Chem.
266:2669-2674 (1991).

165. Dodson, M. S. and Lehman, I. R. Association of DNA helicase and primase
activities with a subassembly of the herpes simplex virus 1 helicase-primase
composed of the UL5 and UL52 gene products. Proc. Natl. Acad. Sci. USA
88:1105-1109 (1991).


166. Crute, J. J. and Lehman, I. R. Herpes Simplex Virus-1 Helicase-Primase.
Physical and Catalytic Properties. J. Biol. Chem. 266:4485-4488 (1991).


167. Hernandez, T. R., Dutch, R. E., Lehman, I. R., Gustafsson, C. and Elias, P.
Mutations in a Herpes Simplex Virus Type 1 Origin That Inhibit Interaction with
Origin-Binding Protein Also Inhibit DNA Replication. J. Virol. 65:1649-1652 (1991)
.

168. Crute, J. J., Bruckner, R. C., Dodson, M. S. and Lehman, I. R. Herpes
Simplex-1 Helicase-Primase: Identification of Two Nucleoside Triphosphatase
Sites that Promote DNA Helicase Action. J. Biol. Chem. 266:21252-21256 (1991)
.

169. Dutch, R. E., Bruckner, R. C., Mocarski, E. S., and Lehman, I. R. Herpes
Simplex Virus Type 1 Recombination: Role of DNA Replication and Viral a
Sequences. J. Virol. 66:277-285 (1992).


170. Bruckner, R.C., Dutch, R.E., Zemelman, B.V., Mocarski, E.S. and Lehman,
I.R. Recombination in vitro between herpes simplex virus type 1 a sequences. Proc.Natl.Acad.Sci. USA 89:10950-10954. (1992)


171. Lehman, I. R. and Kornberg, A. “DNA Replication in Prokaryotes and Eukaryotes.” Chemtracts-Biochemistry and Molecular Biology 3:1-18 (1992).

172. Dodson, M. S. and Lehman, I. R. “The Herpes Simplex Virus Type 1 Origin
Binding Protein: DNA Dependent Nucleoside Triphosphatase Activity.” J. Biol.
Chem. 268:1213-1219 (1993).


173. Boehmer, P. E., Dodson, M.S. and Lehman, I. R. “The Herpes Simplex Virus
Type 1 Origin Binding Protein: DNA Helicase Activity.” J. Biol. Chem. 268:1220-
1225 (1993).


174. Boehmer, P. E. and Lehman, I. R. “Herpes Simplex Virus Type 1 ICP8: Helix-
Destabilizing Properties.” J. Virol. 67:711-715 (1993).


175. Björnberg, O., Bergman, A-C., Rosengren, A. M., Persson, R., Lehman, I. R.
and Nyman, P.E. “dUTPase from Herpes Simplex Virus Type 1; Purification from
Infected Green Monkey Kidney (Vero) Cells and from an Overproducing
Escherichia coli Strain.” Protein Expression and Purification 4:149-159 (1993).


176. Dodson, M. S. and Lehman, I. R. “The Herpes Simplex Virus Type 1 Origin
Binding Protein: DNA Dependent Nucleoside Triphosphatase Activity.” J.
Biol.Chem. 268:1213-1219 (1993).


177. Bortner, C., Hernandez, T. R., Lehman, I. R. and Griffith, Jack. “Herpes
Simplex Virus 1 Single-strand DNA-binding Protein (ICP8) Will Promote
Homologous Pairing and Strand Transfer.” J.Mol.Biol. 231:241-250 (1993).


178. Boehmer, P.E. and Lehman, I.R. Physical interaction between the herpes
simplex virus 1 origin-binding protein and single-stranded DNA-binding protein
ICP8. Proc.Natl.Acad.Sci. USA 90:8444-8448. (1993).


179. Mitsis, P. G., Kowalczykowski, S. C. and Lehman, I. R. “A Single-Stranded
DNA Binding Protein from Drosophila melanogaster: Characterization of the
Heterotrimeric Protein and Its Interaction with Single-Stranded DNA.”
Biochemistry 32:5257-5266 (1993).


180. Chiang, C-S., Mitsis, P. G. and Lehman, I. R. “DNA Polymerase δ from
embryos of Drosophila melanogaster. “ Proc.Natl.Acad.Sci.USA 90:9105-9109
(1993).


181. Dutch, R. E. and Lehman, I. R. “Renaturation of Complementary DNA
Strands by Herpes Simplex Virus Type 1 ICP8.” J. Virol. 67:6945-6949 (1993).


182. Dutch, R. E., Zemelman, B. V. and Lehman, I. R. “Herpes Simplex Virus Type
1 Recombination: The Uc-DR1 Region is Required for High Level α Sequence
Mediated Recombination.” J. Virol. 68:3733-3741 (1994).


183. Skaliter, R. and Lehman, I. R. “Rolling circle DNA replication in vitro by a
complex of herpes simplex virus type 1-encoded enzymes.” Proc. Natl. Acad. Sci.
USA 91:10665-10669 (1994).


184. Boehmer, P. E., Craigie, M. C., Stow, N. D. and Lehman, I. R. “Association of
Origin Binding Protein and Single Strand DNA-binding Protein, ICP8, during Herpes
Simplex Virus Type 1 DNA Replication in vivo.” J.Biol.Chem. 269:29329-29334
(1994).


185. Villani, G., Pillaire, M.-J., and Boehmer, P. E. “Effect of the Major Adduct of
the Antitumor Drug cis-Diamminechloroplatinum (II) on the Activity of Helicase
Essential for DNA Replication, Herpes Simplex Virus Type 1 Origin Binding
Protein.” J. Biol. Chem. 269:21676-21681 (1994).


186. Mitsis, P. G., Chiang, C-S. and Lehman, I. R. “Purification of DNA Polymerase-
Primase (DNA Polymerase α) and DNA Polymerase δ from Embryos of Drosophila
Melanogaster.” DNA Replication volume of Methods in Enzymology. 262:62-85
(1995).


187. Dutch, R. E., Bianchi, V. and Lehman, I. R. “Herpes Simplex Virus Type 1
DNA Replication is Specifically Required for High Frequency Homologous
Recombination between Repeated Sequences.” J. Virol. 69:3084-3089 (1995).


188. Lee, Sam S.-K., Dong, Q., Wang, T.S.-F., and Lehman, I. R. “Interaction of
herpes simplex virus 1 origin-binding protein with DNA polymerase α.” Proc. Natl.
Acad. Sci. USA 92:7882-7886 (1995).


189. Chiang, C.-S. and Lehman, I. R. “Isolation and sequence determination of the
cDNA encoding DNA polymerase δ from Drosophila melanogaster.” Gene
166:237-242 (1995).


190. Crute, J. J., Lehman, I. R., Gambino, J., Yang, T.-F., Medreczky, P., Medreczky,
M., Khan, N. N., Mulder, C., Monroe, J. and Wright, G. E. “Inhibition of Herpes
Simplex Virus Type 1 Helicase-Primase by (Dichloroanilino) Purines and
Pyrimidines.” J. Med. Chem. 38:1820-1825 (1995).


191. Mitsis, P. G. “Phosphorylation and Localization of Replication Protein A.
during Oogenesis and Early Embyogenesis of Drosophila Melanogaster.”
Developmental Biol. 170:445-456 (1995).


192. Skaliter, R., Makhov, A. M., Griffith, J. D. and Lehman, I. R. “Rolling Circle
DNA Replication by Extracts of Herpes Simplex Virus Type 1-Infected Human Cells.”
J. Virol. 70:1132-1136 (1996).


193. Makhov, A. M., Boehmer, P. E., Lehman, I. R. and Griffith, J. D. "The herpes simplex virus type 1 origin-binding protein carries out origin specific DNA unwinding
and forms unwound stem-loop structures." The EMBO Journal 15:1742-1750 (1996).


194. Markov, A.M., Boehmer, P.E. and Lehman, I.R. “Visualization of the Unwinding
of Long DNA Chains by the Herpes Simplex Virus Type 1 UL9 Protein and ICP8. J.
Mol. Biol. 258:789-799 (1996).


195. Sam S.-K. and Lehman, I.R. “Unwinding of the box I element of a herpes simplex virus type 1 origin by a complex of the viral origin binding protein, single-strand DNA binding protein, and single-stranded DNA.” Proc. Natl. Acad. Sci. USA 94:2838-2842 (1997).

196. Boehmer, P.E. and Lehman, I.R. “Herpes Simplex Virus DNA Replication.”
Annu. Rev. Biochem. 66:347-384 (1997).


197. Falkenberg, M., Bushnell, D.A., Elias, P. and Lehman, I. R. “The UL8 Subunit
of the Heterotrimeric Herpes Simplex Virus Type 1 Helicase-Primase Is Required
for the Unwinding of Single Strand DNA-binding Protein (ICP8)-coated DNA
Substrates.” J. Biol. Chem. 272:22766-22770 (1997).


198. Lehman, I.R. “Eukaryotic DNA Repair (Minireview Series)” J. Biol. Chem. 272:23463 (1997).

199. Lehman, I.R. “Recollections of a DNA Enzymologist.” Protein Sci. 7:1061-1066 (1998).

200. Falkenberg, M., Elias, P. and Lehman, I. R. “The Herpes Simplex Virus Type 1
Helicase-primase: ANALYSIS OF HELICASE ACTIVITY ” J. Biol. Chem.
273:32154 - 32157 (1998).


201. Song, B.D. and Lehman, I.R. “Overexpression, Purification, and
Characterization of the Herpes Simplex Virus-1 DNA Polymerase-UL42 Protein Complex.” J. Biochem. Mol. Biol. 31:585-589 (1998).


202. Lee, S., S-K., and Lehman, I.R. “The Interaction of Herpes Simplex Type 1
Virus Origin Binding Protein (UL9 Protein) with Box I, the High Affinity Element
of the Viral Origin of DNA Replication.” J. Biol. Chem. 274:18613-18617 (1999).


203. Lehman, I.R., and Boehmer, P.E. “Replication of Herpes Simplex Virus DNA
(Mini-review).” J. Biol. Chem. 274:28059-28062 (1999).


204. Song, B.D., and Lehman, I.R. “Biochemical Characterization of the Herpes
Simplex Virus-1 DNA Polymerase.” J. Biochem. Mol. Biol. 32:492-496 (1999).

205. Falkenberg, M., Lehman, I.R. and Elias, P. “Leading and Lagging Strand DNA Synthesis in vitro by a reconstituted Herpes Simplex Virus Type 1 replisome. Proc.
Natl. Acad. Sci. USA 97:3896-3900 (2000).


206. He, X. and Lehman, I.R. “Unwinding of a Herpes Simplex Virus Type 1 Origin
of Replication (Oris) by a complex of the Viral Origin Binding Protein and Single
Strand DNA Binding Protein.” J. Virol. 74:5726-5728 (2000).


207. He, Xiaodun and Lehman, I.R. “An initial ATP-independent step in the
unwinding of a herpes simplex virus type I origin of replication by a complex of the
viral origin-binding protein and single-strand DNA binding protein.” Proc. Natl.
Acad. Sci. USA 98:3024-3028 (2001).


208. Eom C.Y. and Lehman IR. “The human DnaJ protein, hTid-1, enhances binding
of a multimer of the herpes simplex virus type 1 UL9 protein to oris, an origin of
viral DNA replication.” Proc. Natl. Acad. Sci. USA 99:1894-1898 (2002).


209. Huang KJ, Zemelman BV, Lehman IR. “Endonuclease G, a candidate human enzyme for the initiation of genomic inversion in herpes simplex type 1 virus.” J.
Biol. Chem. 277:21071-21079 (2002).


210. Makhov AM, Lee SS, Lehman IR, Griffith JD. “Origin-specific unwinding of
herpes simplex virus 1 DNA by the viral UL9 and ICP8 proteins: visualization of
a specific preunwinding complex.” Proc. Natl. Acad. Sci. USA 100:898-903 (2003).


211. Eom CY, Lehman IR. “Replication-initiator protein (UL9) of the herpes simplex virus 1 binds NFB42 and is degraded via the ubiquitin-proteasome pathway.” Proc.
Natl. Acad. Sci. USA 100:9803-9807 (2003).


212. Eom CY, Heo WD, Craske ML, Meyer T, Lehman IR. “The neural F-box
protein NFB42 mediates the nuclear export of the herpes simplex virus type 1
replication initiator protein (UL9 protein) after viral infection.” Proc. Natl. Acad.
Sci. USA 101:4036-4040 (2004).


213. Lehman IR. “Wanderings of a DNA Enzymologist: From DNA Polymerase to
Viral Latency.” Annu Rev Biochem. 75:1-17 (2006).


214. Huang KJ, Ku CC, Lehman IR. “Endonuclease G: a role for the enzyme in recombination and cellular proliferation.” Proc. Natl. Acad. Sci. USA 103:8995-
9000 (2006).

215. Berg, P. and Lehman, I.R. Arthur Kornberg (1918-2007). Science 318:1564
(2007).


216. Lehman, I.R. Historical perspective: Arthur Kornberg, a giant of 20th century biochemistry. TIBS 33:291-296 (2008).